Purpose

Complication of pancreaticoduodenectomy has been regarded as a remarkable concern. The incidence rate of morbidity is relatively high as ever. The aim of this study is to analyze short-term surgical outcomes of pancreaticoduodenectomy performed in a single institution and to investigate risk factors of complication following pancreaticoduodenectomy.

Methods

Medical records of 222 patients who underwent pancreatic resection in between 2013 and 2017 were reviewed retrospectively and clinical data were collected prospectively. We divided the patients into two groups: (1) 159 patients with no complication or complication which scale of Clavien-Dindo was I or II and (2) 63 patients with complication which scale ranged from III to V. We analyzed risk factors for major complication with statistics.

Results

One hundred twelve patients (50.5 %) had at least one complication after pancreaticoduodenectomy and 63 patients (28.4 %) had a major complication. Two patients (0.9 %) died of sepsis after the operation. Old age, male sex, intraoperative blood loss, and soft pancreas were significantly associated with incidence of major complication.

Conclusion

Old age, male sex, intraoperative blood loss, and soft pancreas were risks factors for major complication following pancreaticoduodenectomy. It can be prevented by minimizing blood loss during the operation.